The new Omicron variant of SARS-cov-2 speeding around the world may bring another wave of chaos. It is like walking on a tight rope. The earth is brimming with viruses. The lungs are the paramount respiratory organs. Besides COVID-19, Omicron variant, pollution is another uninvited guest. People are aggrieved by the recurrence of pollution every year. Delhi and most of the cities expressed air emergency. Nothing seems to change. Not a soul is taken care of. The lungs are the organs most affected by COVID‐19. Virus-infected patients are suffering from air hunger. COVID-19 and its variants are the lung annihilate viruses that traumatically lead to lung failure. COVID 19 pandemic sweeps across the globe, Co-infection with respiratory viruses and SARS-CoV-2 and the mutant variants Omicron, raising danger bells around the world. Omicron is an exciting outstanding pandemic co-infected with respiratory viruses, demands crucial public health Intervention.

Keywords: Omicron variant, Monoclonal antibodies, IL-6 antagonists, Covovax “NVX-CoV2373”, AstraZeneca, Nucleic Acid Amplification Test.

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