Cancer is a malignant disease that is the leading cause of death globally. Different prevention and treatment techniques are used to combat such a disease with one of the highest prevalence rates. These include medicine, surgery, conventional chemotherapy, radiation therapy, and some targeted therapies. All these treatments and remedies have proved useful for the results and survival probabilities; however, they have some primary limitations. These limitations, such as multi-drug resistance and non-selective tissue toxicity in drug delivery, sometimes do more harm than healing. To reshape healthcare strategies for cancer, nanotherapeutics is one of the emerging techniques under high experimentation with the least toxic harm observed so far. Nanotherapeutics gives a brand-new frontier for cancer treatment. Nanotechnology has raised the bar by delivering the targeted drug with nano-carriers, effective tumor-targeting nanoparticles, nano-biosensors, and nanomedicines without failure. Advancements in nano-therapeutics have imparted a new horizon through multifaceted applications of nanoparticle usage in nanotechnology. There are also some challenges for modified and functionalized nanomaterials, such as making the correct formulations, enhancing localization, increasing rates of biodistribution, and biocompatibility. Furthermore, this enhanced imaging capacity for cancer diagnosis can be further translated to targeted therapies resulting from these material characteristics. This review summarizes the potential usage of nanoparticles by highlighting their role in targeted drug and gene delivery alongside their vital role in cancer treatment through nano-therapeutics.

Keywords: Cancer, Nanotherapeutics, Nanotechnology, Targeted drug delivery, Nanoparticles, Nano-materials, Cancer treatment, Pharmaceutical, Tumor, Gene therapy, Polymers.

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Source of Funding:

This study has not received any funds from any organization.

Conflict of Interest:

The authors declare that they have no conflict of interest.

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The authors declare that they consented to the publication of this study.

Authors’ Contribution:

All authors contributed equally in this review article.